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Rev. méd. Chile ; 143(6): 809-811, jun. 2015. tab
Article in Spanish | LILACS | ID: lil-753523

ABSTRACT

Thrombotic thrombocytopenic purpura, an immune/non-immune thrombotic microangiopathy (TTP/TMA) is associated with high morbidity and mortality, even with appropriate treatment. In patients refractory to standard treatment with plasmapheresis there is no certainty about the best therapeutic strategy. This report shows our experience in eight refractory patients who survived after treatment with rituximab.


Subject(s)
Adult , Female , Humans , Male , Middle Aged , Young Adult , Purpura, Thrombotic Thrombocytopenic/drug therapy , Rituximab/therapeutic use , Recurrence , Retrospective Studies , Rituximab/pharmacokinetics
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